SCHEMBL1486471

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4251093	0.91	TLR7 (0.52)	TLR7CNR2ESR1ESR2BRD4
	SCHEMBL3866782	0.86	TLR7 (0.43)	TLR7BRD4ALDH1A1LMNAMAPT
	SCHEMBL1486565	0.83	TLR7 (0.46)	TLR7CNR2MTOR
	SCHEMBL1486436	0.81	TLR7 (0.45)	TLR7BRD4LMNAMAPTMEN1
	SCHEMBL1486460	0.80	TLR7 (0.88)	TLR7TLR8
	SCHEMBL22559084	0.80	TLR7 (0.67)	TLR7TLR8
	SCHEMBL3862459	0.80	TLR7 (0.51)	TLR7TLR8SMN1; SMN2
	SCHEMBL19968461	0.78	TLR7 (0.49)	TLR7ESR1ESR2LMNATLR8
	SCHEMBL22559045	0.78	TLR7 (0.68)	TLR7MAPTTLR8
	SCHEMBL4246380	0.77	TLR7 (0.39)	TLR7CNR2BRD4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.