SCHEMBL1486485

SCHEMBL1486485

NCCCCNC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3065839 0.97 PAOX (0.64)
SCHEMBL944344 0.97 PAOX (0.64)
SCHEMBL7007901 0.97 PAOX (0.64)
SCHEMBL1389554 0.97 PAOX (0.64)
SCHEMBL7010487 0.97 PAOX (0.64)
SCHEMBL16247098 0.97 PAOX (0.64)
SCHEMBL7010157 0.97 PAOX (0.64)
SCHEMBL7004889 0.97 PAOX (0.64)
Hydrochloric Acid SCHEMBL4147468 0.97 PAOX (0.58)
Hydrochloric Acid SCHEMBL25353689 0.95 PAOX (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114231551-B Application of protein in promoting apoptosis of insect lymphocytes and/or preventing and controlling pests 云南大学 2023-09-29 CN claimed
CN-114231551-A Application of protein in promoting apoptosis of insect lymphocyte and/or preventing and treating pests 云南大学 2022-03-25 CN claimed
WO-2021217040-A1 CARBAMATE AND UREA DERIVATIVES IMMVENTION THERAPEUTIX (US) 2021-10-28 WO claimed
EP-3686182-A1 CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG Sumitomo Dainippon Pharma Co., Ltd. (JP) 2020-07-29 EP claimed
US-20200207782-A1 CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG SUMITOMO DAINIPPON PHARMA CO., LTD (JP) 2020-07-02 US claimed
CN-105985944-B A kind of new method of intracellular site specific covalent labeled RNA 中国科学院生物物理研究所 2019-05-28 CN claimed
WO-2026088120-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-119899265-A High affinity nanobodies targeting B7H3 (CD 276) for the treatment of multiple solid tumors 美国政府(由卫生和人类服务部的部长所代表) 2025-04-29 CN disclosed
CN-114729041-B High affinity nanobodies targeting B7H3 (CD 276) for the treatment of multiple solid tumors 美国政府(由卫生和人类服务部的部长所代表) 2024-12-31 CN disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2024147060-A1 NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY CELON PHARMA S.A. (PL) 2024-07-11 WO disclosed
WO-2024133853-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS SANOFI (FR) 2024-06-27 WO disclosed
EP-1348710-A1 Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases Apotex Inc. (CA) 2003-10-01 EP disclosed
US-5741799-A ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-04-21 US disclosed
US-5741792-A ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-04-21 US disclosed
US-5583146-A Heterocyclic thrombin inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-10 US disclosed
US-5350864-A Aminoalkylcarbamyl derivatives of forskolin as intermediates for the synthesis of useful forskolin derivatives THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-09-27 US disclosed
EP-0601459-A2 Sulfonamido heterocyclic thrombin inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 1994-06-15 EP disclosed
WO-1991017154-A1 AMINOALKYLCARBAMYL DERIVATIVES OF FORSKOLIN AS INTERMEDIATES FOR THE SYNTHESIS OF USEFUL FORSKOLIN DERIVATIVES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) 1991-11-14 WO disclosed