SCHEMBL7010157

SCHEMBL7010157

NCCCCCCCCCCNC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.64
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 2/20 0.48
MEN1 O00255 1/20 0.48
PLG P00747 1/20 0.48
LMNA P02545 1/20 0.48
THRB P10828 1/20 0.48
SLC6A2 P23975 1/20 0.48
RECQL P46063 1/20 0.48
SLC6A3 Q01959 1/20 0.48
KMT2A Q03164 1/20 0.48
GNAI3 P08754 1/20 0.46
GNAO1 P09471 1/20 0.46
GNAI1 P63096 1/20 0.46
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004889 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL7007901 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL16247098 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL944344 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL1389554 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL3065839 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
SCHEMBL7010487 1.00 PAOX (0.64) PAOXMAOAMAOBALDH1A1ALOX15
Hydrochloric Acid SCHEMBL25353689 0.98 PAOX (0.61) PAOXMAOAMAOBALDH1A1ALOX15
Hydrochloric Acid SCHEMBL15155878 0.98 PAOX (0.61) PAOXMAOAMAOBALDH1A1ALOX15
Ammonia Solution, Strong SCHEMBL8683457 0.98 PAOX (0.61) PAOXMAOAMAOBALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384223-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-06-19 EP disclosed
EP-4384224-A1 CYTOTOXICITY TARGETING CHIMERAS GlaxoSmithKline Intellectual Property Development Limited (GB) 2024-06-19 EP disclosed
WO-2024010776-A1 AGENTS WITH TRANSCRIPTION FACTOR TARGETING MOIETIES BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-01-11 WO disclosed
US-20240002360-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2024-01-04 US disclosed
US-11787778-B2 Bi-functional compounds and methods for targeted ubiquitination of androgen receptor MONTELINO THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
US-20230192643-A1 DIHYDROQUINOLINONES FOR MEDICAL TREATMENT C4 THERAPEUTICS, INC. (US) 2023-06-22 US disclosed
WO-2023076605-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
WO-2023039603-A2 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR MONTELINO THERAPEUTICS, INC. (US) 2023-03-16 WO disclosed
WO-2023017483-A1 CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-02-16 WO disclosed
EP-3917916-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR Montelino Therapeutics, Inc. (US) 2021-12-08 EP disclosed
US-20210332006-A1 CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-10-28 US disclosed
US-20210292298-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2021-09-23 US disclosed
WO-2020160295-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR MONTELINO THERAPEUTICS, LLC (US) 2020-08-06 WO disclosed
US-20200239430-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR MONTELINO THERAPEUTICS, LLC (US) 2020-07-30 US disclosed
US-9447107-B2 Broadly absorbing metalloporphyrin-based multichromophoric arrays for triplet harvesting UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2016-09-20 US disclosed
EP-2697230-A1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C Bristol-Myers Squibb Company (US) 2014-02-19 EP disclosed
WO-2012141704-A1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C BRISTOL-MYERS SQUIBB COMPANY (US) 2012-10-18 WO disclosed
US-20030225007-A1 Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases APOTEX INC. 2003-12-04 US disclosed
EP-1348710-A1 Sulfonamide derivatives of 3-substituted imidazo[1,2-D]-1,2,4-thiadiazoles and 3-substituted-[1,2,4]thiadiazolo[4,5-A]benzimidazole as inhibitors of fibrin cross-linking and transglutaminases Apotex Inc. (CA) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787778-B2 Bi-functional compounds and methods for targeted ubiquitination of androgen receptor AR, ADRM1, PSMA3 PAOX 849/4885MAOA 2016/4885MAOB 2501/4885
US-20230192643-A1 DIHYDROQUINOLINONES FOR MEDICAL TREATMENT CRBN, RBX1, ADRM1 PAOX 2048/4885MAOA 3897/4885MAOB 3570/4885
US-20200239430-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 PAOX 891/4885MAOA 2092/4885MAOB 2614/4885
US-20240002360-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 PAOX 891/4885MAOA 2092/4885MAOB 2614/4885
US-20210332006-A1 CARBON DIOXIDE-REVERSIBLY-PROTECTED CHAIN EXTENSION-CROSSLINKING AGENT AND PREPARATION METHOD AND USE THEREOF MT-CO2, CCNA2, PCNA PAOX 486/4885MAOA 2529/4885MAOB 2796/4885
US-20210292298-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 PAOX 891/4885MAOA 2092/4885MAOB 2614/4885
US-20030225007-A1 Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases PIGS, FGB, SERPINE1 PAOX 2902/4885MAOA 1597/4885MAOB 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.