Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26770885 | 0.91 | LMNA (0.37) | LMNADDAH1 | |
| SCHEMBL3630576 | 0.83 | — | — | |
| SCHEMBL18513347 | 0.83 | — | — | |
| SCHEMBL13304773 | 0.83 | — | — | |
| SCHEMBL1146663 | 0.82 | LMNA (0.47) | LMNA | |
| SCHEMBL21398070 | 0.80 | CYP3A4 (0.33) | LMNADDAH1CYP3A4 | |
| SCHEMBL14559406 | 0.78 | TSHR (0.40) | LMNA | |
| SCHEMBL830509 | 0.76 | LMNA (0.50) | LMNA | |
| SCHEMBL62062 | 0.76 | — | — | |
| SCHEMBL2358 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581366-A1 | Renin Inhibitors | Vitae Pharmaceuticals, Inc. (US) | 2013-04-17 | — | — | EP | disclosed |