Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105467 | 0.70 | KDM5A (0.48) | ALDH1A1MEN1KMT2APAOXTDP1 | |
| SCHEMBL7229020 | 0.70 | PAOX (0.31) | ALDH1A1PAOX | |
| SCHEMBL12330237 | 0.70 | MEN1 (0.32) | ALDH1A1MEN1POLBKMT2AKDM4E | |
| SCHEMBL3339877 | 0.69 | PAOX (0.38) | ALDH1A1MEN1POLBKMT2APAOX | |
| SCHEMBL11587066 | 0.68 | KDM5A (0.47) | ALDH1A1MEN1KMT2APAOXTDP1 | |
| Hydrochloric Acid SCHEMBL866233 | 0.68 | KDM5A (0.47) | ALDH1A1MEN1KMT2APAOXTDP1 | |
| SCHEMBL8204357 | 0.68 | KDM5A (0.47) | ALDH1A1MEN1KMT2APAOXTDP1 | |
| SCHEMBL27575143 | 0.68 | PAOX (0.38) | ALDH1A1MEN1KMT2APAOXKDM4E | |
| SCHEMBL5889011 | 0.67 | — | — | |
| SCHEMBL585434 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581371-A1 | PYRROLYL SUBSTITUTED DIHYDROINDOL-2-ONE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Qilu Pharmaceutical Co., Ltd (CN) | 2013-04-17 | — | — | EP | disclosed |