Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.75 |
| ▸ | CXCR1 | P25024 | 15/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12262739 | 0.90 | CXCR2 (0.78) | CXCR2CXCR1 | |
| SCHEMBL13479631 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL12086735 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL12262533 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL14450102 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL12262734 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL12086739 | 0.87 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL12086757 | 0.87 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL12260486 | 0.86 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL12262551 | 0.86 | CXCR2 (1.00) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485089-B1 | COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES | MERCK SHARP & DOHME (US) | 2013-04-17 | — | — | EP | disclosed |