Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.60 |
| ▸ | FAP | Q12884 | 5/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.60 |
| ▸ | PREP | P48147 | 3/20 | 0.60 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 6/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056862 | 1.00 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL23794392 | 1.00 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL7934986 | 0.89 | DPP4 (0.61) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL19165611 | 0.89 | DPP4 (0.61) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL34461073 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL30729305 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL1647354 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL23045900 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL571628 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL12404687 | 0.87 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368890-B9 | Hepatitis C virus inhibitors | ABBVIE BAHAMAS LTD (BS) | 2013-10-30 | — | — | EP | disclosed |
| EP-2368890-B1 | Hepatitis C virus inhibitors | ABBVIE BAHAMAS LTD (BS) | 2013-04-17 | — | — | EP | disclosed |