Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.55 |
| ▸ | MET | P08581 | 8/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.55 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.55 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 8/20 | 0.38 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072745 | 0.90 | KDR (0.55) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3062338 | 0.89 | MET (0.50) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3069127 | 0.87 | MET (0.49) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3073113 | 0.87 | KDR (0.53) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL14865226 | 0.85 | KDR (0.51) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3071418 | 0.84 | KDR (0.52) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3075031 | 0.84 | KDR (0.52) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3071415 | 0.84 | KDR (0.52) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3081264 | 0.83 | KDR (0.51) | KDRMETNTRK1TEKNTRK3 | |
| SCHEMBL3062783 | 0.80 | KDR (0.44) | KDRMETNTRK1TEKNTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058302-B1 | METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |