Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11959191 | 0.85 | GRM2 (0.52) | GRM2 | |
| SCHEMBL171886 | 0.81 | GRM2 (0.71) | GRM2 | |
| SCHEMBL171274 | 0.73 | GRM2 (0.79) | GRM2 | |
| SCHEMBL2789785 | 0.73 | GRM2 (0.66) | GRM2 | |
| SCHEMBL2454662 | 0.69 | GRM2 (1.00) | GRM2 | |
| SCHEMBL2786838 | 0.69 | GRM2 (0.56) | GRM2 | |
| SCHEMBL13411095 | 0.69 | GRM2 (0.56) | GRM2 | |
| SCHEMBL2789783 | 0.69 | GRM2 (0.74) | GRM2 | |
| SCHEMBL2790979 | 0.69 | GRM2 (0.63) | GRM2 | |
| SCHEMBL171187 | 0.69 | GRM2 (0.54) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994004-B9 | 1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | JANSSEN PHARMACEUTICALS INC (US) | 2013-04-17 | — | — | EP | disclosed |