Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807818 | 0.86 | PTGS2 (0.39) | CNR2PTGS2BDKRB1CNR1NTRK1 | |
| SCHEMBL2806932 | 0.85 | BDKRB1 (0.37) | CNR2ARPTGS2BDKRB1CNR1 | |
| SCHEMBL2807315 | 0.85 | CNR1 (0.36) | CNR2PTGS2BDKRB1CNR1SLC40A1 | |
| SCHEMBL2806879 | 0.85 | BDKRB1 (0.41) | CNR2ARPTGS2BDKRB1CNR1 | |
| SCHEMBL2805268 | 0.84 | BDKRB1 (0.35) | CNR2PTGS2BDKRB1CNR1SLC40A1 | |
| SCHEMBL2810740 | 0.84 | BDKRB1 (0.37) | CNR2PTGS2BDKRB1CNR1NTRK1 | |
| SCHEMBL2805645 | 0.83 | CNR2 (0.34) | CNR2PTGS2BDKRB1CNR1SLC40A1 | |
| SCHEMBL2808456 | 0.83 | CNR1 (0.37) | CNR2ARPTGS2CD38BDKRB1 | |
| SCHEMBL2808286 | 0.83 | BDKRB1 (0.36) | CNR2BDKRB1CNR1JAK1JAK3 | |
| SCHEMBL2806933 | 0.82 | BDKRB1 (0.42) | CNR2PTGS2BDKRB1CNR1JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |