Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSB | P07858 | 5/20 | 0.37 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813315 | 0.94 | BDKRB1 (0.42) | BDKRB1CTSKCTSLCTSBCTSS | |
| SCHEMBL2806425 | 0.89 | BDKRB1 (0.45) | BDKRB1KDM4EALDH1A1 | |
| SCHEMBL14856725 | 0.83 | FAAH (0.45) | MEN1KMT2ATDP1ALPL | |
| SCHEMBL13128611 | 0.83 | BDKRB1 (0.38) | BDKRB1KDM4EALDH1A1 | |
| SCHEMBL13128609 | 0.82 | BDKRB1 (0.38) | BDKRB1ALDH1A1 | |
| SCHEMBL2809229 | 0.81 | BDKRB1 (0.41) | BDKRB1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13128614 | 0.81 | BDKRB1 (0.37) | BDKRB1KDM4EALDH1A1 | |
| SCHEMBL2805859 | 0.81 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL2806522 | 0.80 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL13160124 | 0.80 | BDKRB1 (0.40) | BDKRB1CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |