Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189812 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL5523751 | 0.87 | NPSR1 (0.40) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL21491511 | 0.81 | LMNA (0.32) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL16068213 | 0.80 | MAPT (0.44) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL4825839 | 0.80 | MAPT (0.49) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17392798 | 0.78 | MAPT (0.47) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL5526779 | 0.78 | MAPT (0.51) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17393194 | 0.78 | MAPT (0.43) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5526775 | 0.77 | MAPT (0.50) | NPSR1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL18210 | 0.76 | FFAR3 (0.40) | NPSR1KMT2AMAPTLMNACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |