Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186380 | 0.94 | BDKRB1 (0.37) | MEN1KMT2AMAPTBDKRB1EPHX2 | |
| SCHEMBL186047 | 0.85 | MEN1 (0.43) | MEN1KMT2AMAPTBDKRB1EPHX2 | |
| SCHEMBL2805112 | 0.85 | BDKRB1 (0.37) | BDKRB1KCNH2SCN5ASCN9AHDAC1 | |
| SCHEMBL185963 | 0.84 | FPR2 (0.39) | MEN1KMT2ABDKRB1HDAC1CTSL | |
| SCHEMBL185691 | 0.84 | CNR2 (0.38) | BDKRB1CTSLCTSBCTSS | |
| SCHEMBL186154 | 0.83 | CNR2 (0.37) | BDKRB1EPHX2HDAC1CTSLCTSB | |
| SCHEMBL186861 | 0.83 | CNR2 (0.37) | BDKRB1EPHX2CTSLCTSBCTSS | |
| SCHEMBL13128577 | 0.83 | CNR2 (0.36) | MAPTBDKRB1EPHX2HDAC1CTSL | |
| SCHEMBL2805326 | 0.83 | CNR2 (0.37) | BDKRB1SCN9AHDAC1CTSLCTSB | |
| SCHEMBL186671 | 0.82 | CNR2 (0.37) | BDKRB1CTSLCTSBCTSSCXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |