Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13159819 | 0.87 | CNR2 (0.38) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2809946 | 0.87 | CNR2 (0.39) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2807298 | 0.86 | CNR2 (0.40) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL13160194 | 0.86 | CNR2 (0.33) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2809030 | 0.85 | CNR2 (0.39) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2809043 | 0.84 | CNR2 (0.38) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL19418576 | 0.84 | CNR2 (0.39) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2810010 | 0.84 | RAB9A (0.39) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL13166479 | 0.84 | CNR2 (0.38) | CNR2P2RX7RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2808761 | 0.84 | BDKRB1 (0.40) | CNR2P2RX7RAB9ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |