Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.52 |
| ▸ | CNR1 | P21554 | 15/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508490 | 0.89 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL5521936 | 0.89 | CNR2 (0.55) | CNR2CNR1EGLN2EGLN1EGLN3 | |
| SCHEMBL14215509 | 0.88 | CNR2 (0.56) | CNR2CNR1EGLN2EGLN1EGLN3 | |
| SCHEMBL5516532 | 0.84 | CNR2 (0.53) | CNR2CNR1EGLN2EGLN1EGLN3 | |
| SCHEMBL5516533 | 0.83 | PDE3B (0.49) | CNR2CNR1 | |
| SCHEMBL5508292 | 0.76 | CNR1 (0.67) | CNR2CNR1 | |
| SCHEMBL5513586 | 0.76 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL11922864 | 0.75 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL2745483 | 0.74 | CNR1 (0.68) | CNR2CNR1 | |
| SCHEMBL5508288 | 0.73 | CNR2 (0.62) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |