Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.38 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160089 | 0.90 | MAPK10 (0.42) | EPHX2P2RX7MAPK10PIP5K1CPIK3CA | |
| SCHEMBL13160304 | 0.90 | EPHX2 (0.40) | CYP2C9EPHX2MAPK10PIP5K1CPIK3CA | |
| SCHEMBL13160246 | 0.87 | HTR1A (0.40) | CYP2C9EPHX2P2RX7MAPK10PIP5K1C | |
| SCHEMBL13160140 | 0.83 | CNR2 (0.42) | CYP2C9EPHX2MAPK10MAPK8MAPK14 | |
| SCHEMBL13159674 | 0.81 | MAPK10 (0.44) | EPHX2P2RX7MAPK10PIP5K1CPIK3CA | |
| SCHEMBL185656 | 0.81 | DHODH (0.40) | CNR2 | |
| SCHEMBL13159831 | 0.80 | EPHX2 (0.42) | CYP2C9EPHX2MAPK10PIP5K1CPIK3CA | |
| SCHEMBL13159669 | 0.80 | EPHX2 (0.42) | CYP2C9EPHX2MAPK10PIP5K1CPIK3CA | |
| SCHEMBL13159680 | 0.80 | MAPK10 (0.42) | EPHX2P2RX7MAPK10PIP5K1CPIK3CA | |
| SCHEMBL14865420 | 0.79 | HTR1A (0.41) | CYP2C9EPHX2P2RX7MAPK10PIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |