Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904910 | 0.83 | BLM (0.47) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL125808 | 0.81 | — | — | |
| SCHEMBL19792377 | 0.81 | LMNA (0.47) | TSHRLMNAHSD17B10MAPTHTT | |
| SCHEMBL21164254 | 0.80 | SLC1A1 (0.45) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL3685300 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL3309517 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL121006 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL3584800 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL12951352 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 | |
| SCHEMBL19326985 | 0.80 | TSHR (0.52) | TSHRSLC1A1CA12CA14CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |