Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517062 | 0.93 | ALDH1A1 (0.49) | MAPTGAAALDH1A1CNR1CNR2 | |
| SCHEMBL5525390 | 0.92 | ALDH1A1 (0.45) | MAPTGAAALDH1A1CNR1CNR2 | |
| SCHEMBL5521599 | 0.88 | CNR1 (0.48) | MAPTGAAALDH1A1CNR1CNR2 | |
| SCHEMBL5523022 | 0.88 | CNR1 (0.48) | MAPTGAAALDH1A1CNR1CNR2 | |
| SCHEMBL5525386 | 0.84 | PDE5A (0.46) | MAPTALDH1A1CNR1CNR2SCD | |
| SCHEMBL2746076 | 0.72 | CNR2 (0.73) | ALDH1A1CNR1CNR2SCD | |
| SCHEMBL5525279 | 0.72 | CNR2 (0.67) | ALDH1A1CNR1CNR2SMN1; SMN2 | |
| SCHEMBL5518874 | 0.71 | CNR2 (0.50) | ALDH1A1CNR1CNR2SCDPDE5A | |
| SCHEMBL5542217 | 0.70 | CNR2 (0.64) | CNR1CNR2 | |
| SCHEMBL5512991 | 0.69 | CNR2 (0.57) | ALDH1A1CNR1CNR2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |