Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922699 | 0.89 | CNR2 (0.43) | CNR2CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL11922863 | 0.82 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL5520750 | 0.80 | CNR2 (0.42) | CNR2CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL2745285 | 0.78 | CNR2 (0.43) | CNR2CNR1ALDH1A1KMT2A | |
| SCHEMBL5509591 | 0.78 | CNR2 (0.49) | CNR2CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL5516411 | 0.77 | ALDH1A1 (0.42) | CNR2CNR1ALDH1A1KDM4EGLA | |
| SCHEMBL5517650 | 0.76 | CNR2 (0.48) | CNR2CNR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2746600 | 0.76 | CNR2 (0.48) | CNR2CNR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL5516377 | 0.75 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL5524288 | 0.74 | CNR2 (0.68) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |