Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17031906 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL27272428 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL1850656 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL1336739 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL3050914 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL8337646 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL4847115 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL4840543 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| SCHEMBL14053968 | 0.99 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ACEPREP | |
| Cesium SCHEMBL8725844 | 0.97 | CHRM2 (0.44) | CHRM2CHRM1CHRM3ACEPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692157-B1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE | VERTEX PHARMA (US) | 2013-04-17 | — | — | EP | disclosed |