Sugi Predict

Sugi Predict / Compounds / SCHEMBL1336739

SCHEMBL1336739

SCHEMBL1336739

CC(C)(C)OC(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 1/20 0.45
▸ CHRM1 P11229 1/20 0.45
▸ CHRM3 P20309 1/20 0.45
▸ ACE P12821 7/20 0.44
▸ PREP P48147 4/20 0.42
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ USP2 O75604 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.39
▸ CYP3A4 P08684 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ GPR119 Q8TDV5 1/20 0.37
▸ EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14053968 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL1850656 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL27272428 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL17031906 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL3050914 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL8337646 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL4840543 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL4847115 1.00 CHRM2 (0.45) CHRM2CHRM1CHRM3ACEPREP
SCHEMBL14865498 0.99 CHRM2 (0.44) CHRM2CHRM1CHRM3ACEPREP
Cesium SCHEMBL8725844 0.99 CHRM2 (0.44) CHRM2CHRM1CHRM3ACEPREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 — — EP disclosed
EP-3533797-B1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2023-12-20 — — EP disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 — — US disclosed
US-11718638-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2023-08-08 — — US disclosed
WO-2022253101-A1 PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR 上海优理惠生医药有限公司 2022-12-08 — — WO disclosed
US-20220348558-A1 INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES UT RESEARCH FOUNDATION 2022-11-03 — — US disclosed
US-20220119400-A1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2022-04-21 — — US disclosed
US-11248000-B2 Quinazoline and indole compounds to treat medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2022-02-15 — — US disclosed
EP-3939591-A1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS Achillion Pharmaceuticals, Inc. (US) 2022-01-19 — — EP disclosed
US-20070021484-A1 Substituted N-cinnamyl benzamides CHEMOCENTRYX, INC. (US) 2007-01-25 — — US disclosed
US-20070021484-A1 Substituted N-cinnamyl benzamides CHEMOCENTRYX, INC. (US) 2007-01-25 — — US disclosed
WO-2007002842-A2 SUBSTITUTED N-CINNAMYL BENZAMIDES CHEMOCENTRYX, INC. (US) 2007-01-04 — — WO disclosed
EP-1615885-A1 B -FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS Warner-Lambert Company LLC (US) 2006-01-18 — — EP disclosed
US-20050143427-A1 [B]-fused bicyclic proline derivatives and their use for treating arthritic conditions BARVIAN NICOLE C (US) 2005-06-30 — — US disclosed
WO-2004092132-A1 [B]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS WARNER-LAMBERT COMPANY LLC (US) 2004-10-28 — — WO disclosed
US-5506237-A PROLYL-ENDOPEPTIDASE INHIBITOR; USEFUL FOR TREATING OR PREVENTING MEMORY LOSS DUE TO AGING, ANXIETY AND DEPRESSION ADIR ET COMPAGNIE (FR) 1996-04-09 — — US disclosed
US-4965250-A TETRAPEPTIDE; IMMUNE SYSTEM ACTIVATION ADIR ET CIE (FR) 1990-10-23 — — US disclosed
US-4725581-A NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS ADIR ET COMPAGNIE (FR) 1988-02-16 — — US disclosed
US-4720484-A Peptide compounds having a nitrogenous polycyclic structure ADIR S.A.R.L. (FR) 1988-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348558-A1 INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES NEFM, EIF2AK2, PMP22 CHRM2 4520/4885CHRM1 4532/4885CHRM3 4531/4885
US-11718638-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT CHRM2 4024/4885CHRM1 3580/4885CHRM3 3179/4885
US-11248000-B2 Quinazoline and indole compounds to treat medical disorders CFB, TFPI, MAOB CHRM2 773/4885CHRM1 998/4885CHRM3 856/4885
US-20220119400-A1 QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS CFB, TFPI, MAOB CHRM2 773/4885CHRM1 998/4885CHRM3 856/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CHRM2 4580/4885CHRM1 3968/4885CHRM3 4501/4885
US-20050143427-A1 [B]-fused bicyclic proline derivatives and their use for treating arthritic conditions PRAP1, PRR12, PPIB CHRM2 4822/4885CHRM1 4803/4885CHRM3 4830/4885
US-20070021484-A1 Substituted N-cinnamyl benzamides BRDT, BCCIP, NAT10 CHRM2 4871/4885CHRM1 4881/4885CHRM3 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.