SCHEMBL1486561

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1486467	0.89	IP6K1 (0.48)	IP6K1NMT1NMT2MEN1NPC1
	SCHEMBL1486520	0.88	IP6K1 (0.45)	IP6K1NMT1NMT2MEN1NPC1
	SCHEMBL1486525	0.84	TLR7 (0.57)	TLR7
	SCHEMBL1486536	0.82	MEN1 (0.41)	IP6K1TLR7PDE4APDE4BPDE4C
	SCHEMBL4541234	0.82	MAPT (0.44)	IP6K1NMT1NMT2MEN1RAB9A
	SCHEMBL1486618	0.82	IP6K1 (0.43)	IP6K1NMT1NMT2MEN1NPC1
	SCHEMBL1486592	0.80	TLR7 (0.44)	TLR7PDE10A
	SCHEMBL1486756	0.80	NMT1 (0.44)	IP6K1NMT1NMT2MEN1RAB9A
	SCHEMBL30710541	0.79	TLR7 (0.60)	TLR7PDE4APDE4BPDE4CPDE4D
	SCHEMBL19968181	0.79	TLR7 (0.44)	TLR7PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.