SCHEMBL14865789

SCHEMBL14865789

CCO[Si](CCCNCC(O)COCCC[Si](C)(C)OC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
CASR P41180 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16280855 0.91 KDM4E (0.38) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL14865748 0.90 KDM4E (0.36) KDM4ECASRALDH1A1KMT2A
SCHEMBL9606976 0.89 KDM4E (0.38) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL16280900 0.88 KDM4E (0.42) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL18635974 0.88 KDM4E (0.37) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL9606985 0.86 KDM4E (0.38) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL18623801 0.85 KDM4E (0.37) KDM4ECASRALDH1A1KMT2ASMN1; SMN2
SCHEMBL62207 0.83 KDM4E (0.41) KDM4ECASRALDH1A1KMT2AUSP2
SCHEMBL14865775 0.82 KDM4E (0.34) KDM4ECASRALDH1A1KMT2A
SCHEMBL19697514 0.81 KDM4E (0.36) KDM4ECASRALDH1A1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096776-B2 Silicone release coating composition of condensation reaction curing type SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-04 US disclosed
US-20130096257-A1 SILICONE RELEASE COATING COMPOSITION OF CONDENSATION REACTION CURING TYPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-18 US disclosed