Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9606976 | 0.97 | KDM4E (0.38) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL16280900 | 0.95 | KDM4E (0.42) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL18623801 | 0.94 | KDM4E (0.37) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL16280855 | 0.87 | KDM4E (0.38) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL14865789 | 0.86 | KDM4E (0.36) | KDM4EUSP2CASRALDH1A1SMN1; SMN2 | |
| Propene SCHEMBL28263032 | 0.85 | USP2 (0.40) | KDM4EUSP2HTTCASRCYP1A2 | |
| SCHEMBL18635974 | 0.83 | KDM4E (0.37) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL19697514 | 0.80 | KDM4E (0.36) | KDM4EUSP2HTTCASRALDH1A1 | |
| SCHEMBL18324099 | 0.78 | KDM4E (0.35) | KDM4ECASR | |
| SCHEMBL62207 | 0.77 | KDM4E (0.41) | KDM4EUSP2HTTCASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170074449-A1 | MODIFIED HYBRID SILICA AEROGELS | MIDCAP FUNDING IV TRUST | 2017-03-16 | — | — | US | disclosed |
| US-9512287-B2 | Modified hybrid silica aerogels | ASPEN AEROGELS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150065590-A1 | MODIFIED HYBRID SILICA AEROGELS | MIDCAP FUNDING IV TRUST | 2015-03-05 | — | — | US | disclosed |
| US-8906973-B2 | Modified hybrid silica aerogels | ASPEN AEROGELS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120136079-A1 | MODIFIED HYBRID SILICA AEROGELS | ASPEN AEROGELS, INC. (US) | 2012-05-31 | — | — | US | disclosed |