Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.62 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.59 |
| ▸ | CALCA | P06881 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740098 | 0.89 | CALCRL (0.72) | CALCRLRAMP1CALCA | |
| SCHEMBL13740094 | 0.89 | CALCRL (0.72) | CALCRLRAMP1CALCA | |
| SCHEMBL13739797 | 0.85 | CALCRL (0.70) | CALCRLRAMP1CALCA | |
| SCHEMBL1670796 | 0.85 | CALCRL (0.59) | CALCRLRAMP1CALCA | |
| SCHEMBL30231314 | 0.85 | CALCRL (0.59) | CALCRLRAMP1CALCA | |
| SCHEMBL1670764 | 0.85 | CALCRL (0.59) | CALCRLRAMP1CALCA | |
| SCHEMBL30231300 | 0.85 | CALCRL (0.59) | CALCRLRAMP1CALCA | |
| SCHEMBL30721808 | 0.83 | CALCRL (0.72) | CALCRLRAMP1CALCA | |
| SCHEMBL12206966 | 0.83 | CALCRL (0.75) | CALCRLRAMP1CALCA | |
| SCHEMBL13832480 | 0.82 | CALCRL (0.54) | CALCRLRAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748429-B2 | CGRP receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748429-B2 | CGRP receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-06-10 | — | — | US | disclosed |
| US-20130096130-A1 | CGRP Receptor Antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2013-04-18 | — | — | US | disclosed |
| US-20130096130-A1 | CGRP Receptor Antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096130-A1 | CGRP Receptor Antagonists | CALCRL, BDKRB2, CALCR | CALCRL 1/4885RAMP1 130/4885CALCA 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.