SCHEMBL14866426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14866151	0.90	ALK (0.81)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL14866202	0.89	ALK (0.85)	ALKINSRIGF1REGFRFGFR1
	Tae-684 SCHEMBL282775	0.89	ALK (1.00)	ALKINSRIGF1REGFRFGFR1
	Tae-684 SCHEMBL29641017	0.89	ALK (1.00)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL18018790	0.88	ALK (0.79)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL14866424	0.88	ALK (0.78)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL14866223	0.88	ALK (0.78)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL11979353	0.87	ALK (0.85)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL21150935	0.87	ALK (0.82)	ALKINSRIGF1REGFRFGFR1
	SCHEMBL3955128	0.87	ALK (0.81)	ALKINSRIGF1REGFRFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.