SCHEMBL14868705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13584612	0.84	EPHX1 (0.59)	APEX1EPHX1EPHX2LMNAPOLB
	SCHEMBL29518499	0.84	EPHX1 (0.59)	APEX1EPHX1EPHX2LMNAPOLB
	Hydrochloric Acid SCHEMBL13584366	0.83	EPHX1 (0.57)	APEX1EPHX1EPHX2LMNAPOLB
	SCHEMBL14868756	0.81	TSHR (0.53)	EPHX1LMNAPOLBALDH1A1GAA
	SCHEMBL14868691	0.79	GAA (0.51)	LMNAALDH1A1GAAHPGDKMT2A
	SCHEMBL14868432	0.79	SNCA (0.37)	APEX1POLBCYP3A4ALDH1A1GAA
	SCHEMBL20315920	0.79	SMN1; SMN2 (0.49)	APEX1EPHX1EPHX2LMNACYP3A4
	SCHEMBL891282	0.78	EPHX1 (0.52)	APEX1EPHX1EPHX2LMNACYP3A4
	Hydrochloric Acid SCHEMBL9668292	0.77	EPHX1 (0.50)	APEX1EPHX1EPHX2LMNACYP3A4
	Chlorproguanil SCHEMBL44783	0.76	EPHX1 (0.46)	APEX1EPHX1EPHX2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.