SCHEMBL148718

SCHEMBL148718

[CH]=CCCC=CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148717 1.00
SCHEMBL29284410 0.97
SCHEMBL29284544 0.89 TOP1 (0.34)
SCHEMBL29284280 0.87 TOP1 (0.38)
SCHEMBL29284495 0.83 ALDH1A1 (0.39)
SCHEMBL29284283 0.83 TOP1 (0.34)
SCHEMBL3101667 0.82
SCHEMBL242590 0.82
SCHEMBL3632234 0.82
SCHEMBL147635 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143757-B Multifunctional compound, composition and application of degradable BTK kinase 杭州和正医药有限公司 2024-07-05 CN disclosed
CN-115175967-B Ionic liquids for stabilizing viscosity of silicate-based coatings 巴斯夫欧洲公司 2024-06-14 CN disclosed
CN-118119588-A Precursors for phenolic aromatic compounds 奇华顿股份有限公司 2024-05-31 CN disclosed
WO-2023190410-A1 COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, COLOR FILTER, PARTITION WALL AND IMAGE DISPLAY DEVICE 三菱ケミカル株式会社 2023-10-05 WO disclosed
US-20230042328-A1 IONIC LIQUID FOR STABILIZING VISCOSITY OF SILICATE-BASED COATINGS BASF SE (DE) 2023-02-09 US disclosed
CN-109422749-B Pyrimidinedione derivative for inhibiting monocarboxylic acid transporter 重庆医药工业研究院有限责任公司 2023-01-24 CN disclosed
CN-115175967-A Ionic liquids for stabilizing viscosity of silicate-based coatings 巴斯夫欧洲公司 2022-10-11 CN disclosed
CN-109715605-B Process for preparing carotenoid monoesters 巴斯夫欧洲公司 2022-04-12 CN disclosed
CN-109320509-B FXR receptor agonists 轩竹生物科技股份有限公司 2022-02-08 CN disclosed
CN-108602811-B FXR receptor agonists 轩竹生物科技有限公司 2021-11-16 CN disclosed
EP-0565683-A1 QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS SCHERING AKTIENGESELLSCHAFT (DE) 1993-10-20 EP disclosed
WO-1993008173-A1 QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-29 WO disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
US-4845100-A WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
US-4755598-A 1'-(substituted)ethyl-7β-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]methyl]ceph-3-em-4-carboxylate derivatives having antibacterial utility TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-07-05 US disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 EP disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed
EP-0128028-A2 Cephalosporin derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1984-12-12 EP disclosed