Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14872911 | 0.84 | BCL2L1 (0.45) | CA1CA2CA9ALDH1A1TAS1R3 | |
| SCHEMBL14872909 | 0.81 | CA1 (0.44) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL2897153 | 0.77 | CYP46A1 (0.47) | CA1CA2CA9ALDH1A1HPGD | |
| SCHEMBL13927744 | 0.76 | POLB (0.56) | ALDH1A1POLBTAS1R3TAS1R1ABCB1 | |
| SCHEMBL14872912 | 0.76 | AVPR2 (0.51) | ALDH1A1POLBHPGDLMNA | |
| SCHEMBL14872910 | 0.73 | CA1 (0.44) | CA1CA2CA9ALDH1A1ABCB1 | |
| SCHEMBL14872933 | 0.69 | HPGD (0.51) | ALDH1A1POLBHPGDLMNA | |
| SCHEMBL11100086 | 0.69 | PTGS1 (0.43) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL11100090 | 0.69 | PTGS1 (0.43) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL14394702 | 0.69 | MEN1 (0.62) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013054351-A1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2013-04-18 | — | — | WO | disclosed |