Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571408 | 0.83 | TAS1R3 (0.46) | POLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4171511 | 0.79 | POLB (0.52) | POLBUTS2RLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL24571390 | 0.79 | HPGD (0.53) | POLBLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL24567577 | 0.79 | HPGD (0.53) | POLBLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14872913 | 0.76 | CA1 (0.39) | POLBLMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4175755 | 0.76 | TAS1R3 (0.53) | LMNATAS1R3TAS1R1TAS1R2HPGD | |
| SCHEMBL4166757 | 0.76 | TAS1R3 (0.53) | LMNATAS1R3TAS1R1TAS1R2HPGD | |
| SCHEMBL4766299 | 0.76 | SMN1; SMN2 (0.57) | POLBUTS2RLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL13407497 | 0.74 | SMN1; SMN2 (0.55) | POLBUTS2RSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL4169088 | 0.74 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2MEN1KMT2ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | POLB 4329/4885UTS2R 1338/4885LMNA 3147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.