Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.72 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14873156 | 0.85 | GPR119 (0.74) | GPR119HSD11B1 | |
| SCHEMBL2555906 | 0.84 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2555904 | 0.84 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12283335 | 0.84 | GPR119 (1.00) | GPR119 | |
| SCHEMBL14873081 | 0.84 | GPR119 (0.49) | GPR119HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL14873089 | 0.82 | GPR119 (0.48) | GPR119HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL14873175 | 0.82 | GPR119 (0.48) | GPR119HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL14873077 | 0.81 | GPR119 (0.47) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873092 | 0.80 | GPR119 (0.48) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873080 | 0.79 | GPR119 (0.52) | GPR119CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013055910-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-04-18 | — | — | WO | disclosed |