Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.47 |
| ▸ | CA1 | P00915 | 10/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19028602 | 1.00 | CA2 (0.47) | CA2CA1CA9CA12CA7 | |
| SCHEMBL28486619 | 1.00 | CA2 (0.47) | CA2CA1CA9CA12CA7 | |
| Hydrochloric Acid SCHEMBL28210759 | 0.98 | CA2 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL275812 | 0.98 | TP53 (0.47) | CA2CA1CA9CA12CA7 | |
| Hydrochloric Acid SCHEMBL28419791 | 0.96 | TP53 (0.45) | CA2CA1CA9CA12CA7 | |
| Hydrochloric Acid SCHEMBL28418644 | 0.96 | TP53 (0.45) | CA2CA1CA9CA12CA7 | |
| SCHEMBL24665746 | 0.91 | CA2 (0.50) | CA2CA1CA9CA12CA7 | |
| SCHEMBL277861 | 0.91 | CA2 (0.45) | CA2CA1CA9CA12CA7 | |
| SCHEMBL20542290 | 0.91 | CA2 (0.50) | CA2CA1CA9CA12CA7 | |
| SCHEMBL20074598 | 0.91 | CA2 (0.50) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072864-B | TDO2 inhibitors | 基因泰克公司 | 2022-05-27 | — | — | CN | claimed |
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | claimed |
| EP-3394068-A1 | TDO2 INHIBITORS | Genentech, Inc. (US) | 2018-10-31 | — | — | EP | claimed |
| WO-2017107979-A1 | TDO2 INHIBITORS | GENENTECH, INC. (US) | 2017-06-29 | — | — | WO | claimed |
| CN-120141972-A | Method for separating and enriching 24 perfluorinated compounds in water environment | 桂林理工大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-115010712-A | TDO2 inhibitors | 基因泰克公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-110072864-B | TDO2 inhibitors | 基因泰克公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112566901-A | Phenyl-substituted pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112292373-A | Pyridylpyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | disclosed |
| EP-3394068-A1 | TDO2 INHIBITORS | Genentech, Inc. (US) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017107979-A1 | TDO2 INHIBITORS | GENENTECH, INC. (US) | 2017-06-29 | — | — | WO | disclosed |
| CN-102796081-A | Pyrimidine sulphonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB | 2012-11-28 | — | — | CN | disclosed |
| CN-101048401-B | Pyrimidine sulfonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB | 2012-09-12 | — | — | CN | disclosed |
| EP-2311827-A1 | Thiopyrimidine derivative, useful as an intermediate for chemokine receptor modulators. | AstraZeneca AB (SE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2301933-A1 | Thiopyrimidine derivative, useful as an intermediate for chemokine receptor modulators | AstraZeneca AB (SE) | 2011-03-30 | — | — | EP | disclosed |
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |
| CN-101048401-A | Pyrimidine sulfonamide derivatives as chemokine receptor modulators | ASTRAZENECA AB (SE) | 2007-10-03 | — | — | CN | disclosed |