SCHEMBL148739

SCHEMBL148739

CC(=CNC(N)=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
TSHR P16473 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
POLB P06746 2/20 0.45
CYP3A4 P08684 2/20 0.45
PARP1 P09874 1/20 0.45
CYP2C19 P33261 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
HSD17B10 Q99714 1/20 0.45
DEGS1 O15121 1/20 0.42
CES1 P23141 3/20 0.42
CES2 O00748 2/20 0.42
GAA P10253 1/20 0.41
KDM1A O60341 1/20 0.41
MTNR1A P48039 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039410 0.93 ALDH1A1 (0.44) ALDH1A1LMNAMAPTL3MBTL1TSHR
SCHEMBL11116138 0.79 TSHR (0.48) ALDH1A1LMNAMAPTTSHRPOLB
SCHEMBL11116142 0.79 TSHR (0.48) ALDH1A1LMNAMAPTTSHRPOLB
SCHEMBL13770099 0.75 KDM1A (0.46) ALDH1A1LMNAMAPTL3MBTL1TSHR
SCHEMBL16018391 0.74 TSHR (0.50) ALDH1A1LMNAMAPTL3MBTL1TSHR
SCHEMBL976775 0.74 TSHR (0.50) ALDH1A1LMNAMAPTL3MBTL1TSHR
SCHEMBL20037284 0.73 KDM1A (0.42) ALDH1A1LMNAMAPTL3MBTL1TSHR
SCHEMBL11279520 0.72 DEGS1 (0.41) ALDH1A1LMNAMAPTTSHRTDP1
SCHEMBL11279517 0.72 DEGS1 (0.41) ALDH1A1LMNAMAPTTSHRTDP1
SCHEMBL22810989 0.69 KDM1A (0.40) MAPTTSHRTDP1POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10279069-B2 Shape memory polymer articles with a microstructured surface 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-05-07 US disclosed
EP-2046556-B1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2015-11-18 EP disclosed
US-8236226-B2 Methods for changing the shape of a surface of a shape memory polymer article 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-07 US disclosed
US-20120058305-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M INNOVATIVE PROPERTIES COMPANY 2012-03-08 US disclosed
US-20110198781-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY 2011-08-18 US disclosed
US-7951319-B2 Methods for changing the shape of a surface of a shape memory polymer article 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-31 US disclosed
EP-2046408-A1 SHAPE MEMORY POLYMER ARTICLES WITH A MICROSTRUCTURED SURFACE 3M Innovative Properties Company (US) 2009-04-15 EP disclosed
EP-2046556-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M Innovative Properties Company (US) 2009-04-15 EP disclosed
WO-2008014167-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-31 WO disclosed
US-20080023890-A1 METHODS FOR CHANGING THE SHAPE OF A SURFACE OF A SHAPE MEMORY POLYMER ARTICLE 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed
EP-0583259-B1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING MINNESOTA MINING & MFG (US) 1996-01-31 EP disclosed
US-5475124-A Fluorosilane compounds useful as terminating agents in anionic siloxane polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-12-12 US disclosed
US-5314748-A Radiation-curable silicone elastomers and pressure sensitive adhesives MINNESOTA MINING & MANUFACTURING COMPANY (US) 1994-05-24 US disclosed
EP-0583259-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING. MINNESOTA MINING & MFG (US) 1994-02-23 EP disclosed
EP-0576544-A1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS. MINNESOTA MINING & MFG (US) 1994-01-05 EP disclosed
US-5264278-A Low temperature adhesion, shock resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-23 US disclosed
US-5237082-A Amine subsituted fluorosilanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-17 US disclosed
WO-1992016590-A1 RADIATION CURABLE VINYL/SILICONE RELEASE COATING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
WO-1992016593-A2 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-01 WO disclosed
US-5091483-A Controllability and stability of rapidly-cured telechelic polymers containing ethylenic, amido, ester and/or urea groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-25 US disclosed