SCHEMBL14874657

SCHEMBL14874657

CCOC(=O)C(Cc1ccccc1OC)(C(C)C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
ITGA4 P13612 1/20 0.42
ITGB7 P26010 1/20 0.42
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HTT P42858 2/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 2/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
PLIN1 O60240 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
PLIN5 Q00G26 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874591 0.84 MEN1 (0.45) MEN1KMT2AITGA4ITGB7TSHR
SCHEMBL14874414 0.83 MEN1 (0.46) MTNR1AMTNR1BMEN1KMT2AITGA4
SCHEMBL14874580 0.81 MEN1 (0.46) MTNR1AMTNR1BMEN1KMT2ATSHR
SCHEMBL14874577 0.81 MEN1 (0.46) MTNR1AMTNR1BMEN1KMT2ATSHR
SCHEMBL14874601 0.81 HTT (0.43) MEN1KMT2AITGA4ITGB7TSHR
SCHEMBL29798733 0.81 MEN1 (0.48) MTNR1AMTNR1BMEN1KMT2ATSHR
SCHEMBL14874337 0.81 MEN1 (0.48) MTNR1AMTNR1BMEN1KMT2ATSHR
SCHEMBL29798734 0.81 MEN1 (0.48) MTNR1AMTNR1BMEN1KMT2ATSHR
SCHEMBL14874632 0.81 MEN1 (0.44) MTNR1AMTNR1BMEN1KMT2AITGA4
SCHEMBL14874327 0.80 MEN1 (0.46) MTNR1AMTNR1BMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 EP disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 EP disclosed