SCHEMBL14874580

SCHEMBL14874580

CCOC(=O)C(Cc1ccccc1OC)(C(C)(C)C)C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 4/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
PLIN1 O60240 1/20 0.43
POLB P06746 1/20 0.43
PLIN5 Q00G26 1/20 0.43
ABHD5 Q8WTS1 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 1/20 0.42
CNR2 P34972 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MMP8 P22894 1/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874577 0.86 MEN1 (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL29798733 0.85 MEN1 (0.48) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874337 0.85 MEN1 (0.48) MEN1KMT2AMAPTLMNAHTT
SCHEMBL29798734 0.85 MEN1 (0.48) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874327 0.84 MEN1 (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874556 0.84 MEN1 (0.47) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874497 0.82 MEN1 (0.44) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874324 0.81 MEN1 (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874657 0.81 MTNR1A (0.44) MEN1KMT2AMAPTLMNAHTT
SCHEMBL14874447 0.81 MMP8 (0.50) MEN1KMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 EP disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 EP disclosed