SCHEMBL14874841

SCHEMBL14874841

CC(C)(C)OC(=O)ON1CCC(c2nc(COc3ccc(-n4cnnn4)cc3F)cs2)CC1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874967 0.92 GPR119 (0.63) GPR119
SCHEMBL14874865 0.90 GPR119 (0.60) GPR119
SCHEMBL14874940 0.90 GPR119 (0.57) GPR119
SCHEMBL1118035 0.90 GPR119 (0.78) GPR119
SCHEMBL14874928 0.88 GPR119 (0.79) GPR119
SCHEMBL14874979 0.87 GPR119 (0.49) GPR119
SCHEMBL14874835 0.85 GPR119 (0.54) GPR119
SCHEMBL14874855 0.85 GPR119 (0.62) GPR119
SCHEMBL14874908 0.83 GPR119 (0.75) GPR119
SCHEMBL14874926 0.82 GPR119 (0.53) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2111107-B1 HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS METABOLEX INC (US) 2013-04-24 EP claimed