Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789575 | 0.93 | GPR119 (0.38) | GPR119CPT2CPT1ACPT1BFAAH | |
| SCHEMBL14874911 | 0.88 | GPR119 (0.54) | GPR119CPT2CPT1ACPT1B | |
| SCHEMBL1118481 | 0.88 | GPR119 (0.53) | GPR119FAAH | |
| SCHEMBL14874949 | 0.88 | GPR119 (0.45) | GPR119 | |
| SCHEMBL14874871 | 0.88 | GPR119 (0.39) | GPR119CPT2CPT1ACPT1B | |
| SCHEMBL14874966 | 0.88 | GPR119 (0.39) | GPR119CPT2CPT1ACPT1BFAAH | |
| SCHEMBL14874974 | 0.87 | GPR119 (0.38) | GPR119CPT2CPT1ACPT1B | |
| SCHEMBL14874880 | 0.87 | GPR119 (0.41) | GPR119 | |
| SCHEMBL14874824 | 0.85 | GPR119 (0.37) | GPR119CPT2CPT1ACPT1B | |
| SCHEMBL14874898 | 0.82 | GPR119 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111107-B1 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS | METABOLEX INC (US) | 2013-04-24 | — | — | EP | claimed |