SCHEMBL1487526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8313448	0.89	MAP4K1 (0.71)	LRRK2MAP4K1IL2CLK1DYRK1A
	SCHEMBL31235685	0.83	MAPK1 (0.59)	MAP4K1IL2MAPK1CLK1DYRK1A
	SCHEMBL1487564	0.79	MAP4K1 (0.47)	LRRK2MAP4K1IL2MAPK1CLK1
	SCHEMBL30524645	0.79	LRRK2 (0.62)	LRRK2MAP4K1IL2MAPK1CLK1
	SCHEMBL8321878	0.78	ROCK1 (0.58)	MAP4K1IL2MAPK1CLK1DYRK1A
	SCHEMBL13753992	0.78	KDR (0.53)	LRRK2CDK2GSK3BBMPR1BKDR
	SCHEMBL13746422	0.78	ACVR1 (0.53)	LRRK2CDK2GSK3BBMPR1BKDR
	SCHEMBL30524641	0.78	PIK3C3 (0.53)	LRRK2MAP4K1IL2MAPK1CLK1
	SCHEMBL18892042	0.77	MAP4K1 (0.47)	LRRK2MAP4K1IL2MAPK1CLK1
	SCHEMBL3411072	0.76	LRRK2 (0.62)	LRRK2MAP4K1IL2MAPK1CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.