Pyridine

Pyridine

SCHEMBL1487591

CCCCOS(=O)(=O)C(F)(F)F.c1ccncc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.40
CA2 P00918 12/20 0.40
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C9 P11712 3/20 0.35
TSHR P16473 3/20 0.35
CYP2C19 P33261 3/20 0.35
CYP1A2 P05177 2/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA9 Q16790 8/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA12 O43570 3/20 0.34
CA7 P43166 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA5B Q9Y2D0 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL1487597 0.94 CA1 (0.43) CA1CA2TSHRCA9CA12
Pyridine SCHEMBL27983879 0.91 CA2 (0.38) CA1CA2TSHR
SCHEMBL777643 0.86 CA2 (0.52) CA1CA2CYP3A4TSHRCA9
SCHEMBL27930318 0.84 CA1 (0.50) CA1CA2CYP3A4TSHRCA9
Fluoride SCHEMBL27893472 0.84 CA1 (0.50) CA1CA2CYP3A4TSHRCA9
SCHEMBL27912318 0.84 CA1 (0.50) CA1CA2CYP3A4TSHRCA9
SCHEMBL29170929 0.84 CA1 (0.50) CA1CA2CYP3A4TSHRCA9
Pyridine SCHEMBL6283510 0.82 TSHR (0.35) CA1CA2TSHR
SCHEMBL38550 0.80 CA1 (0.54) CA1CA2TSHRCA9CA12
Pyridine SCHEMBL28000309 0.79 CA1 (0.41) CA1CA2TSHRCA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110053230-A1 METHOD FOR CONTROLLING RATE OF LOWERING MOLECULAR WEIGHT OF POLYSACCHARIDES CONTAINED IN CELLULOSIC BIOMASS, AND METHOD FOR PRODUCING SUGAR, ALCOHOL, OR ORGANIC ACID TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-03-03 US disclosed
WO-2004080974-A1 A PURIFICATION METHOD OF IONIC LIQUIDS TO OBTAIN THEIR HIGH PURITY CHEMTECH RESEARCH INCORPORATION (KR) 2004-09-23 WO disclosed