Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727878 | 0.94 | PRKCA (0.40) | PRKCAKDM1ACYP19A1L3MBTL1BACE1 | |
| SCHEMBL12727879 | 0.92 | PRKCA (0.42) | PRKCAKDM1ACYP19A1L3MBTL1BACE1 | |
| Alnuside B SCHEMBL22796510 | 0.81 | PPARG (0.49) | CYP3A4HSD17B10PPARGPPARDPPARA | |
| Alnuside B SCHEMBL12672476 | 0.81 | PPARG (0.49) | CYP3A4HSD17B10PPARGPPARDPPARA | |
| Oregonin SCHEMBL29389089 | 0.79 | PPARG (0.46) | CYP3A4PPARGPPARDPPARA | |
| Oregonin SCHEMBL12659728 | 0.79 | PPARG (0.46) | CYP3A4PPARGPPARDPPARA | |
| SCHEMBL12659725 | 0.71 | PPARG (0.40) | CYP3A4ALOX15MAPK1HSD17B10PPARG | |
| SCHEMBL22796348 | 0.70 | PPARG (0.40) | CYP3A4PPARGPPARDPPARA | |
| SCHEMBL22796193 | 0.70 | PPARG (0.42) | CYP19A1CYP3A4ALOX15MAPK1HSD17B10 | |
| SCHEMBL24993777 | 0.69 | PRKCA (0.51) | PRKCACYP19A1CYP3A4HSD17B10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426370-B2 | Diaryl hepatonoid-based compounds and use thereof | RNL BIO CO., LTD. (KR) | 2013-04-23 | — | — | US | disclosed |