Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877646 | 0.87 | HSD17B10 (0.68) | MEN1KMT2AHSD17B10ESR1NPC1 | |
| SCHEMBL14877640 | 0.87 | HSD17B10 (0.58) | MEN1KMT2AHSD17B10GLAESR1 | |
| SCHEMBL11537116 | 0.86 | HSD17B10 (0.61) | MEN1KMT2AHSD17B10GLAESR1 | |
| SCHEMBL12387087 | 0.83 | ESR1 (0.65) | MEN1KMT2AHSD17B10ESR1ALDH1A1 | |
| SCHEMBL13478270 | 0.83 | CA9 (0.52) | MEN1KMT2AHSD17B10ESR1NPC1 | |
| SCHEMBL7594849 | 0.81 | MEN1 (0.54) | MEN1KMT2AHSD17B10ESR1NPC1 | |
| SCHEMBL13018340 | 0.80 | MEN1 (0.53) | MEN1KMT2AHSD17B10ESR1NPC1 | |
| SCHEMBL9516311 | 0.80 | HSD17B10 (0.77) | MEN1KMT2AHSD17B10ALDH1A1POLB | |
| SCHEMBL13018341 | 0.80 | MEN1 (0.53) | MEN1KMT2AHSD17B10ESR1NPC1 | |
| SCHEMBL13018338 | 0.80 | MEN1 (0.53) | MEN1KMT2AHSD17B10ESR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426092-B2 | Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors | XEROX CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |