SCHEMBL14877646

SCHEMBL14877646

CC(=O)Oc1cccc(N2C(=O)c3ccc(-c4ccc5c(c4)C(=O)N(C)C5=O)cc3C2=O)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.68
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.54
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
NPC1 O15118 1/20 0.54
TLR9 Q9NR96 1/20 0.54
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
HTT P42858 1/20 0.46
ESR1 P03372 1/20 0.45
MAPK1 P28482 1/20 0.44
GAA P10253 1/20 0.43
ACHE P22303 1/20 0.43
BRD4 O60885 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14877713 0.88 HSD17B10 (0.76) HSD17B10ALDH1A1LMNAKMT2AMEN1
SCHEMBL14877657 0.87 MEN1 (0.52) HSD17B10ALDH1A1LMNAKMT2AMEN1
SCHEMBL10601959 0.84 HSD17B10 (0.73) HSD17B10ALDH1A1LMNAKMT2AMEN1
SCHEMBL7570223 0.81 HSD17B10 (1.00) HSD17B10ALDH1A1LMNAKMT2AMEN1
SCHEMBL14010063 0.80 BRD4 (0.48) HSD17B10ALDH1A1KMT2AMEN1ESR1
SCHEMBL14010052 0.80 BRD4 (0.51) HSD17B10ALDH1A1KMT2AMEN1NPC1
SCHEMBL11892525 0.79 BRD4 (0.50) HSD17B10ALDH1A1KMT2AMEN1TLR9
SCHEMBL759684 0.79 HSD17B10 (0.54) HSD17B10ALDH1A1LMNAKMT2AMEN1
SCHEMBL12034649 0.79 MAPK1 (0.56) HSD17B10ALDH1A1KMT2AMEN1NPC1
SCHEMBL12639229 0.78 MGLL (0.57) HSD17B10ALDH1A1KMT2AMEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426092-B2 Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors XEROX CORPORATION (US) 2013-04-23 US disclosed
US-8426092-B2 Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors XEROX CORPORATION (US) 2013-04-23 US disclosed