SCHEMBL14877708

SCHEMBL14877708

CC[C@H](C)[C@H](N)CN(C(=O)[C@H]1C[C@@H]1c1cccc(F)n1)c1ccc(-c2ccc(OC(C)C)cc2)cc1

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR88 Q9GZN0 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1667199 1.00 GPR88 (0.91) GPR88
SCHEMBL12212366 0.92 GPR88 (0.79) GPR88
SCHEMBL6889750 0.89 GPR88 (0.76) GPR88
SCHEMBL1666810 0.88 GPR88 (0.91) GPR88
SCHEMBL14877710 0.88 GPR88 (0.91) GPR88
SCHEMBL14877724 0.88 GPR88 (0.91) GPR88
SCHEMBL1666648 0.88 GPR88 (0.91) GPR88
SCHEMBL6891711 0.87 GPR88 (1.00) GPR88
SCHEMBL1666808 0.87 GPR88 (0.73) GPR88
SCHEMBL2516828 0.87 GPR88 (1.00) GPR88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426414-B2 Modulators of G protein-coupled receptor 88 BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-23 US disclosed