Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 9/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878173 | 0.85 | ABL1 (0.49) | EGFRF2ENPP1 | |
| SCHEMBL14878151 | 0.85 | F2 (0.47) | F2TDP1L3MBTL1 | |
| SCHEMBL14878175 | 0.84 | MEN1 (0.48) | F2 | |
| SCHEMBL8088156 | 0.83 | F2 (0.44) | ALDH1A1LMNASMN1; SMN2EGFRMAPT | |
| SCHEMBL14878116 | 0.81 | F2 (0.55) | F2 | |
| SCHEMBL14878177 | 0.79 | F2 (0.43) | ALDH1A1MAPTF2RAB9A | |
| SCHEMBL14878156 | 0.79 | F2 (0.52) | F2 | |
| SCHEMBL8143174 | 0.78 | F2 (0.41) | ALDH1A1LMNASMN1; SMN2EGFRMAPT | |
| SCHEMBL14878182 | 0.78 | F2 (0.44) | ALDH1A1MAPTF2TDP1L3MBTL1 | |
| SCHEMBL6069317 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNASMN1; SMN2EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426433-B2 | Anticoagulant compounds, pharmaceutical compositions on their basis to treat thrombotic conditions, and plasma-substituting solution to correct hypercoagulation defects of hemodilution | Obschestvo S Ogranichennoi Otvetsttvennoctiyu “Bionika” (RU) | 2013-04-23 | — | — | US | disclosed |