SCHEMBL14878705

SCHEMBL14878705

c1ccc(N(c2ccc(Nc3ccc(N(c4ccccc4)c4ccc5ccccc5c4)cc3)cc2)c2ccc3ccccc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
HSD17B10 Q99714 4/20 0.60
CYP3A4 P08684 4/20 0.60
HPGD P15428 2/20 0.60
MAPT P10636 6/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
ALOX12 P18054 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPK1 P28482 2/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
PTGS2 P35354 1/20 0.43
HTR2B P41595 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28424995 0.98 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL23277214 0.98 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL30805718 0.98 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL23561391 0.98 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL28389125 0.96 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL4893481 0.96 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL13175097 0.96 ALDH1A1 (0.66) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL14407385 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL17283628 0.93 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP3A4HPGDMAPT
SCHEMBL13780628 0.93 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP3A4HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2096690-B1 Organic electroluminescence device UDC IRELAND LTD (IE) 2013-04-24 EP disclosed