Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.74 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134613 | 0.93 | IL6 (0.84) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL4580423 | 0.91 | IL6 (0.72) | IL6GRIN1GRIN2B | |
| SCHEMBL447694 | 0.91 | IL6 (0.70) | IL6GRIN1GRIN2B | |
| SCHEMBL4582012 | 0.90 | IL6 (0.79) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL1917741 | 0.89 | IL6 (0.89) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL4581163 | 0.89 | IL6 (0.82) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL4127299 | 0.89 | IL6 (0.82) | IL6HTR2C | |
| SCHEMBL13639359 | 0.89 | IL6 (0.69) | IL6GRIN1GRIN2B | |
| SCHEMBL4129581 | 0.88 | IL6 (0.76) | IL6GRIN1GRIN2BHTR2C | |
| SCHEMBL4580821 | 0.88 | IL6 (0.76) | IL6GRIN1GRIN2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151436-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE WHICH HAS, AS SUBSTITUENT, PHENYL GROUP HAVING SULFONIC ACID ESTER STRUCTURE OR SULFONIC ACID AMIDE STRUCTURE INTRODUCED THEREIN AND HAS GLUCOCORTICOID RECEPTOR-BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-04-24 | — | — | EP | disclosed |