Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825143 | 1.00 | KDM4E (0.48) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13388314 | 0.90 | CHRM2 (0.42) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10263182 | 0.88 | KDM4E (0.51) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13379419 | 0.87 | CHRM2 (0.41) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15958552 | 0.75 | KDM4E (0.56) | KDM4ECHRM1LMNAGAACYP2D6 | |
| SCHEMBL14477939 | 0.74 | KDM4E (0.51) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18526734 | 0.72 | KDM4E (0.50) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31008738 | 0.72 | TP53 (0.37) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31009076 | 0.72 | TP53 (0.37) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31009097 | 0.72 | TP53 (0.37) | KDM4ECHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242750-B1 | CONFORMATIONALLY RESTRICTED BIPHENYL DERIVATIVES FOR USE AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-04-24 | — | — | EP | disclosed |