Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009097 | 1.00 | TP53 (0.37) | TP53CHRNA7KCNH2CHRM3CHRM2 | |
| SCHEMBL31009076 | 1.00 | TP53 (0.37) | TP53CHRNA7KCNH2CHRM3CHRM2 | |
| SCHEMBL31009174 | 0.82 | VNN1 (0.34) | CHRNA7KCNH2ALDH1A1KDM4EVNN1 | |
| SCHEMBL31009148 | 0.82 | VNN1 (0.34) | CHRNA7KCNH2ALDH1A1KDM4EVNN1 | |
| SCHEMBL31009132 | 0.82 | VNN1 (0.34) | CHRNA7KCNH2ALDH1A1KDM4EVNN1 | |
| SCHEMBL9966003 | 0.79 | CHRNA7 (0.41) | TP53CHRNA7KCNH2CHRM3CYP1A2 | |
| SCHEMBL9965990 | 0.79 | CHRNA7 (0.41) | TP53CHRNA7KCNH2CHRM3CYP1A2 | |
| SCHEMBL30499323 | 0.78 | CYP2C19 (0.38) | TP53CHRNA7KCNH2CHRM3CYP1A2 | |
| SCHEMBL14879164 | 0.72 | KDM4E (0.48) | CHRNA7KCNH2CHRM3CHRM2CHRM4 | |
| SCHEMBL825143 | 0.72 | KDM4E (0.48) | CHRNA7KCNH2CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118201915-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2024-06-14 | — | — | CN | disclosed |