Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879424 | 0.81 | PTGS2 (0.51) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL3489600 | 0.76 | PTGS2 (0.55) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL16487838 | 0.75 | PTGS1 (0.51) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL22643385 | 0.75 | PTGS2 (0.51) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL14879518 | 0.73 | PTGS2 (0.50) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL14561938 | 0.73 | PTGS2 (0.55) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL18986024 | 0.73 | PTGS2 (0.52) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL10202049 | 0.72 | PTGS2 (0.51) | PTGS1PTGS2ALOX5STIM1ORAI1 | |
| SCHEMBL333569 | 0.72 | PIK3CD (0.41) | RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL21332382 | 0.72 | PTGS2 (0.52) | PTGS1PTGS2ALOX5STIM1ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768810-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013059666-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-04-25 | — | — | WO | disclosed |