Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 11/20 | 1.00 |
| ▸ | AMY1A | P0DUB6 | 11/20 | 1.00 |
| ▸ | GAA | P10253 | 11/20 | 1.00 |
| ▸ | SI | P14410 | 11/20 | 1.00 |
| ▸ | MGAM2 | Q2M2H8 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.70 |
| ▸ | F12 | P00748 | 5/20 | 0.62 |
| ▸ | ELANE | P08246 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433519 | 1.00 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL16706437 | 0.84 | MGAM (0.77) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29433322 | 0.83 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL2493561 | 0.83 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728230 | 0.83 | MGAM (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28836634 | 0.83 | MGAM (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27397036 | 0.77 | F12 (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29996413 | 0.76 | MGAM (0.61) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL2491371 | 0.76 | MGAM (0.79) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL3900498 | 0.75 | KCNMA1 (0.81) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |